Liver biopsy is often taken to rule out a problem with the liver. It is required to determine various liver conditions like jaundice, hepatitis, and also cirrhosis or cancer.
Liver biopsy is a small surgical procedure that requires collecting the liver tissue as a sample. This sample is studied further in the laboratory for finding out the exact cause of the disease.In most cases, liver biopsy is an outpatient procedure. Only in rare cases, the patient would need hospitalization. However, before the procedure, the patient has to go through screening for the biopsy and it has to be deemed that the surgical procedure would cause no harm to the patient.
A liver biopsy is a very helpful procedure, and in several cases it provides a correct understanding of the problem. Once the doctor has a proper understanding of the disease, treating the person becomes easy and more effective. There are hundreds of liver conditions that can cause death if left undiagnosed. Sometimes diseases like jaundice may be just an after effect of the real underlying problem. Liver biopsies are also done on overweight patients, and to solve nonalcoholic fatty liver disease. Through the tissue culture the doctor can determine the extent of damage on the liver and what kind of treatment plan has to be taken in order to cure the patient. Several people think that biopsies are conducted only to determine if the patient has cancer. That is not true, especially in the case of the liver.
Once the biopsy results are obtained, the laboratory will grade it. There are different grading methods for liver biopsy results, but the most common are Metavir and Knodell methods. The Metavir grading for liver biopsy results is mostly used for patients suffering from hepatitis C. The grading shows the amount of inflammation present in the liver, and this denoted as a numeric value ranging from 0 to 4. The 0 stands for no inflammation, while 3 or 4 shows severe inflammation.
The Knodell grading for liver biopsy results is also known as histologic activity index. This method is usually used to find out what stage the liver disease is at. Although a complicated procedure, the Knodell method is considered to quite accurate in terms of showing the damage and inflammation present in the liver. The scoring system is also different, and ranges from 0 to 18, with 0 being no inflammation, and 18 being severe inflammation.
More Articles :