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Ultram Medication And Lab Results

    Ultram is composed of a centrally acting synthetic opioid analgesic drug known as Tramadol hydrochloride. Ultram was approved by the FDA in 1998 for the treatment of chronic lower back pain.

     Effects of Ultram were studied in three long-term controlled trials that involved a total of 820 patients. Out of these, 530 patients received Ultram. Apart from that, double-blind trials were conducted in patients with a variety of chronic painful conditions so as to study the efficacy of the drug in controlling pain.

      In the first study, 129-132 patients were selected per group. This was a randomized, blinded clinical trial where groups were administered with an Ultram dose of 200 mg per day. The dosage started with 50 mg per day and was gradually increased by 50 mg every 3 days. Very few patients complained of symptoms like dizziness and vertigo. Similar results were obtained in a second trail with 54-59 patients, where Ultram dose started with 25 mg per day and was gradually increased by 25 mg every third day to 100 mg per day. Later, the dose was taken up to 200 mg per day with an increment of 50 mg per day.

      So as to study the adverse reactions involving the usage of Ultram, a double blind randomized clinical trails were conducted in 550 patients. Out of these, 375 patients were more than 60-65 years of age. Adverse reactions in patients were observed on 7, 30 and 90 days and tabulated. As per the results, the most frequent reactions were those occurring in the central nervous system and gastrointestinal system. As a control for this study, one group was administered with 300 mg of acetaminophen along with 30 mg of codeine phosphate and another group was given 325 mg of aspirin with 30 mg of codeine phosphate. The results obtained in the test group were similar to those obtained in control groups. While most number of patients had symptoms of dizziness, nausea, constipation, headache and somnolence, symptoms like sweating, dyspepsia, dry mouth, asthenia and diarrhea were less common.

Ultram Medication And Lab Results

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