Generic composition of Risperdal is known as Risperidone, a psychotropic agent belonging to the chemical class of benzisoxazole derivatives. Antipsychotic effect of Risperdal occurs due to reduction of dopamine secretion by the brain causing a regulated balance of neurotransmitter chemicals in the brain. Risperdal has been approved by the US Food and Drug Administration (FDA) for the treatment of Schizophrenia. In fact, Risperdal is the only USFDA approved drug available for the treatment of schizophrenia and bipolar disorder in children between the ages 10-18. Risperdal is also recommended for the treatment of irritability associated with autistic disorder in children and adolescents aged 5-16 years.
Risperdal is not recommended for elderly patients suffering with dementia-related psychosis. This is because atypical antipsychotic drugs such as Risperdal cause an increased risk of death in such individuals. The most common side effects of Risperdal are similar to other atypical antipsychotic drugs. These include somnolence, increased appetite, fatigue, weakness, rhinitis, vomiting, excessive coughing, uncontrollable urination, increased saliva, low blood pressure, constipation, fever, tremors, muscle stiffness, abdominal pain, anxiety, nausea, dry mouth, dizziness and indigestion.
Like all other antipsychotics, Risperdal can cause potentially dangerous and incurable side effects such as Tardive Dyskinesia (TD), extrapyramidal symptoms (EPS) and neuroleptic malignant syndrome (NMS). Risperdal can also cause diabetes, hypertension and other serious conditions of glucose metabolism including Ketoacidosis and hyperosmolar coma. Risperdal is strictly not recommended for pregnant and lactating women.
In spite of its potential risks involved, this drug continues to be a blockbuster medicine in the market for the past 8 years primarily due to prescription of doctors who continue to be unaware of its potential dangers and take risk rather than looking at safer alternatives. Recently, manufacturers have issue a warning indicating the potential side effects of the drug in patients. One can file a product liability lawsuit against Janssen Pharmaceutica if he has suffered from dangerous side effects of Risperdal that include stroke, NMS and TD.
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