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Long Term Side Effects Of Ultram

      Mode of action of Ultram is dependant on its binding to specific opoid receptors present in the central nervous system of the human body. Opoid receptors are important for transmitting the sensation of pain from the entire body to the central nervous system. Ultram blocks the uptake of norepinephrine and serotonin in the body, thereby altering the pain message to the brain. However, Ultram is not known to have any anti-inflammatory effect similar to a non-steroidal anti-inflammatory drug nor does it cause building up of drug tolerance in patients as is the case with any narcotic compound.

       However, there are certain side effects associated with long term usage of Ultram. Patient using Ultram for an extended period get physically and mentally addicted to the drug. As a result of fundamental changes in the brain caused due to Ultram, patient suffers with impaired pain tolerance in the body. Ultram addicts can get rid of the habit by undergoing an expensive and painful drug detoxification program. Detoxification is done through administration of other drugs such as methadone, Valium, Clonidine, naltrexone and levo-alpha-acetyl-methadol (LAAM). Naltrexone is a proper narcotic antagonist that blocks the activation of opiate receptors and helps the brain to recover from the damages caused by Ultram. Usage of Ultram along with antidepressant drugs causes an increased incidence of seizures and epilepsy.

      Ultram should never be prescribed to pregnant and breast-feeding mothers unless it is absolutely required. Research suggests that Ultram influences the development of fetal brain. Nursing mothers should discontinue breast feeding while taking Ultram as this drug passes through the breast milk and may affect the infant.

     Ultram can be fatal if taken in excess. Overdose of Ultram causes difficulty in breathing, dizziness, drowsiness, seizures, chest pain, cardiac arrest and coma.

Long Term Side Effects Of Ultram

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