Beating Severe PsoriasisIt is estimated that around 10 million people in the US suffer from varying degrees of psoriasis. This is a chronic skin condition where the outer layer of the skin becomes scaly and extremely itchy. Sometimes, due to constant itching, painful open patches of sores are formed.
In some people, psoriasis can be controlled by using topical medicated ointments and lotions.
Psoriasis can be debilitating condition. It is painful and can affect a person's movements. In addition, it also affects the person psychologically. The person will have low self-esteem and will not be able to move in social environments.
Although many believe that psoriasis is a skin disorder affecting the epidermis, it is not a fact. Researchers found out in 1979 that this condition is actually an immune system disorder. This knowledge and discovery revolutionized the treatment for psoriasis. Today, patients can get relief from the symptoms through drugs that target the immune response.
Basically doctors now know that psoriasis is caused due to a disorder of the T-cells. These are cells found in the blood and they cause an allergic reaction in the skin. Psoriasis is caused when the T-cells become overactive.
Moderate to severe psoriasis is treated using medications like cyclosporine and methotrexate. These systemic drugs work very well in controlling the symptoms of psoriasis, but cannot be used for a long period of time as they have a toxic effect on the other organs of the body.
A form of light treatment known as PUVA is also very effective in treating severe psoriasis. However, many patients find it inconvenient to take this treatment as they need to come into the doctor's office two to three times a week for several months together. However, even PUVA is known to have side effects.The latest method of treating severe psoriasis is using new class of drugs that basically targets the immune response of the body. The drugs stop the action between the T-cells and another cell known as antigen-presenting cell. It is this antigen-presenting cell that is responsible for lesions that develop due to psoriasis. Depending on the type of drug being administered, it can either be injected subcutaneously or intravenously. Thanks to these drugs, it is now possible to beat severe psoriasis.