Hemophilia And The Lymphatic System

Hemophilia And The Lymphatic System

The blood is the one of the most vital tissues in the body and it comprises of RBCs, WBCs, platelets and plasma. The platelets present in the blood are responsible for causing the blood to clot and coagulate when an injury occurs. When a person is suffering from hemophilia, the clotting function of the blood is affected and this causes abnormal bleeding as the blood takes a long time to clot.

Hemophilia is X-linked hereditary disease which is passed on from a female onto her male offsprings. There are primarily 2 kinds of hemophilia, Hemophilia A and Hemophilia B. The former is caused to absence of clotting factor VIII, while the latter is caused due to absence of clotting factor IX. (See Reference 1)

So, you might be wondering how are hemophilia and the lymphatic system connected. The lymphatic system is responsible for the production of WBCs, or the white blood cells. Also, lymph, which is the lymphatic fluid, begins as blood plasma. When a person is suffering from hemophilia, the person is often given blood transfusion. This makes the person more vulnerable to blood-related diseases and infections. Generally, hemophiliacs are more susceptible to catching HIV or AIDS when they get regular blood transfusion. (See Reference 2) So, doctors keep a close watch at the lymphatic system to get an indication whether the hemophiliac is suffering from AIDS or HIV. Generally, when a person gets either of these infections, the lymph nodes tend to swell up and get inflamed. This swelling gives an indication to the doctor the person may have contracted HIV or AIDS and the necessary treatment is started immediately.

More Articles :

Hemophilia And The Lymphatic System 1. Amgen: Blood And Lymphatic System
https://www.baybio.org/pdf/impact08_blood.pdf

2. National Library Of Medicine: Assessment of Lymph Node Size in Hemophiliac Children
https://www.ncbi.nlm.nih.gov/pubmed/3473425