|Graph Of Onset And Duration Of Insulin
Presence or absence of insulin inside the human body determines the fate of several metabolic pathways including the regulation of glucose and fat levels in the blood. In case of normal individuals, insulin is secreted in different amounts at different times depending on the requirement by a specialized organ called as pancreas.
In case of individuals suffering from diabetes mellitus, body does not make insulin or does not secrete insulin in sufficient amounts. In such individuals, intake of insulin as a supplement is essential in order to maintain the normal body metabolism.
Currently, there are several forms of insulin that are available in the market. However, the fact is that not all types of insulin are equal nor they are created in a similar manner. Hence, it is very important to determine the right type of insulin for a particular individual. There are three primary characteristics that define the types of insulin. These include onset, peak time and duration.
- Onset: This is the time required by the insulin to begin the process of lowering blood glucose levels.
- Peak Time: This is the time when the injected insulin activity is at its peak.
- Duration: This is the total length of time insulin remains effective after injecting.
When a graph is drawn taking into consideration all these three characteristics, it usually comes in the form of a peak. Depending on these peaks, one can evaluate the efficacy of insulin. Short-acting and rapid-acting insulin types such as Humalog and 50/50 premix usually have a sharp and definable peak. Sharp peaks indicate short duration time. In case of insulin types that are intermediate-acting such as Lente insulins, peaks are long and flat showing a slow but sustained rate of decline. As the peak goes flatter, more is the duration period of the insulin type.
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